[Theory] 8/29 Thesis Defense: Ben Lai, TTIC

[Mary Marre via Theory]

*When*:    Thursday, August 29th from* 9**:00am - 10:00am CT*

*Where*:   Talk will be given *live, in-person* at
               TTIC, 6045 S. Kenwood Avenue
               5th Floor, *Room 530*

*Virtually*: via *Zoom*
<https://uchicagogroup.zoom.us/j/91558909586?pwd=naSjIsRrL2Gj4ksOL0i3ZAa3miUjab.1>


*Who:  *    Ben Lai, TTIC


*Title:* Leveraging deep generative model for computational protein design
and optimization
*Abstract: *Recent advancements in deep learning have significantly
improved in silico protein modeling. While these developments are
promising, there still lacks a comprehensive computational framework for
protein design. Such a framework would aim to address a broad spectrum of
design challenges. I will introduce a novel generative model for protein
structures, and an iterative design framework for computational protein
engineering. Applications demonstrate success in challenging protein design
problems such as de novo fold generation, functional protein optimization,
motif scaffolding, and antibody design within a flexible, machine-driven
approach.

*Thesis Committee:* Jinbo Xu (Thesis Advisor), Avrim Blum, Aly Khan




Mary C. Marre
Faculty Administrative Support
*Toyota Technological Institute*
*6045 S. Kenwood Avenue, Rm 517*
*Chicago, IL  60637*
*773-834-1757*
*mmarre at ttic.edu <mmarre at ttic.edu>*
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