<div dir="ltr"><div class="gmail_default" style=""><p style="font-size:small;color:rgb(80,0,80);font-variant-numeric:normal;font-variant-east-asian:normal;font-stretch:normal;line-height:normal;margin:0px"><font face="arial, sans-serif" color="#000000"><font style="vertical-align:inherit"><font style="vertical-align:inherit"><b>When:</b>    </font></font><font style="vertical-align:inherit"><font style="vertical-align:inherit">  Friday, May 14th at<b> <span style="background-color:rgb(255,255,0)">2:00 pm CT</span></b></font></font><br></font></p><p class="MsoNormal" style="font-size:small;margin:0in 0in 0.0001pt;color:rgb(80,0,80);line-height:normal;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial"><font face="arial, sans-serif" color="#000000"> </font></p><p class="MsoNormal" style="font-size:small;margin:0in 0in 0.0001pt;color:rgb(80,0,80);line-height:normal;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial"><font face="arial, sans-serif"><font style="color:rgb(0,0,0);vertical-align:inherit"><font style="vertical-align:inherit"><b>Where:</b>     </font></font><font color="#000000">Zoom Virtual <span class="gmail-il">Talk</span> (</font><font color="#0000ff"><b><a href="https://uchicagogroup.zoom.us/webinar/register/WN_k3Hb0Ab2TzqZWdqo8Wh7DQ" target="_blank">register in advance here</a></b></font><font color="#000000">)</font></font></p><p class="MsoNormal" style="font-size:small;margin:0in 0in 0.0001pt;color:rgb(80,0,80);line-height:normal;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial"><font face="arial, sans-serif" color="#000000"> </font></p><p class="MsoNormal" style="font-size:small;margin:0in 0in 0.0001pt;line-height:normal;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial"><font face="arial, sans-serif" style=""><font style="vertical-align:inherit"><font style="vertical-align:inherit"><font color="#000000"><b style="">Who: </b> </font><font color="#500050">    </font><font color="#000000">  </font></font></font></font><font color="#000000">Derek Reiman, <span style="font-family:arial,sans-serif">University of Illinois at Chicago</span></font></p><p class="MsoNormal" style="font-size:small;margin:0in 0in 0.0001pt;color:rgb(80,0,80);line-height:normal;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial"><br></p><p style="color:rgb(60,64,67);letter-spacing:0.2px;white-space:pre-wrap"><font face="arial, sans-serif" style=""><b style="">Title:       </b>Deep Learning Frameworks for Multi-omics Analyses of the Microbiome in Disease Studies</font></p><p style="color:rgb(60,64,67);letter-spacing:0.2px;white-space:pre-wrap"><font face="arial, sans-serif"><b>Abstract: </b>Over the last decade, our understanding of the functions of the microbiome has greatly increased. In particular, the microbiome of the gut has been shown to play a critical role in the development of multiple metabolic related diseases.As such, clinicians have looked to the microbiome as a potential target for therapeutic interventions by either directly altering the microbiome composition or targeting underlying metabolic functions. In this talk, I will introduce integrative deep learning frameworks addressing challenges in microbiome studies. First, I will discuss a convolutional neural network framework that integrates microbial abundance with the underlying community taxonomic structure for the identification of microbial biomarkers associated with specific diseases. Second, I will present an interpretable deep neural network framework integrating microbiome and metabolomic data to facilitate the clustering of microbes and metabolites into functionally related modules. I will conclude by discussing my future research direction involving the integration of external stimuli, imaging, and single cell sequencing data tobetter model microbiome dynamics and functions.</font></p><p style="color:rgb(60,64,67);letter-spacing:0.2px;white-space:pre-wrap"><font face="arial, sans-serif"><b>Bio: </b>Derek Reiman is a PhD candidate at the University of Illinois at Chicago. Hisdoctoral research focuses on developing new deep learning frameworks for multi-omics analyses of the host-microbiome interface. His work has been supported by grants from the NVIDIA Corporation and by UIC’s College of MedicinePre-doctoral Education for Clinical and Translational Sciences program.Previously, he spent time interning at Tempus Labs in the Immunology group,where he focused on developing deep learning models for integrating gene expression and imaging data. His research interests lie in developing interpretable deep learning models for biology.</font></p><h1 class="gmail-nova-e-text gmail-nova-e-text--size-xl gmail-nova-e-text--family-sans-serif gmail-nova-e-text--spacing-none gmail-nova-e-text--color-grey-900" style="color:rgb(17,17,17);margin:0px;line-height:1.2;border:0px;padding:0px"><font face="arial, sans-serif" style="" size="2">Host:<span style="font-weight:400"> <a href="mailto:j3xu@ttic.edu">Jinbo Xu</a></span></font></h1><p class="MsoNormal" style="font-size:small;margin:0in 0in 0.0001pt;color:rgb(80,0,80);line-height:normal;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial"><br></p><p class="MsoNormal" style="font-size:small;margin:0in 0in 0.0001pt;color:rgb(80,0,80);line-height:normal;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial"><br></p><p class="MsoNormal" style="font-size:small;margin:0in 0in 0.0001pt;color:rgb(80,0,80);line-height:normal;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial"><br></p><p class="MsoNormal" style="font-size:small;margin:0in 0in 0.0001pt;color:rgb(80,0,80);line-height:normal;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial"><br></p></div><div><div dir="ltr" class="gmail_signature" data-smartmail="gmail_signature"><div dir="ltr"><div dir="ltr"><div dir="ltr"><div dir="ltr"><div dir="ltr"><div dir="ltr"><div dir="ltr"><font face="arial, helvetica, sans-serif">Mary C. Marre</font><div><font face="arial, helvetica, sans-serif">Faculty Administrative Support</font></div><div><i><font face="arial, helvetica, sans-serif" color="#3d85c6"><b>Toyota Technological Institute</b></font></i></div><div><i><font face="arial, helvetica, sans-serif" color="#3d85c6">6045 S. Kenwood Avenue</font></i></div><div><i><font face="arial, helvetica, sans-serif" color="#3d85c6">Chicago, IL  60637</font></i><br></div><div><b><i><a href="mailto:mmarre@ttic.edu" target="_blank"><font face="arial, helvetica, sans-serif">mmarre@ttic.edu</font></a></i></b><br></div></div></div></div></div></div></div></div></div></div></div>