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<div class="gmail_default" style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;text-decoration-style:initial;text-decoration-color:initial;background-color:rgb(255,255,255)"><font face="arial, helvetica, sans-serif"><span style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;text-decoration-style:initial;text-decoration-color:initial"><font color="#000000" face="arial, helvetica, sans-serif">When:     Monday, March 12th <span class="gmail-m_-2908798825741450181gmail-m_-4002343983082707046gmail-m_7108663852680761240gmail-m_8932996379216170455gmail-m_7943440058048769724gmail-m_6885163803304591797gmail-m_1291990161734276046gmail-m_-5366141555987907539gmail-m_7288451293410119657gmail-m_7014796927259893518gmail-m_-5237592048697853688gmail-m_-2847741945628619148gmail-m_-681226243108775954gmail-m_-4338767794047815756gmail-m_7960197898027616883gmail-m_8692226636264124041gmail-m_2794822896869921223gmail-m_7508998950622620526gmail-m_-7153355664495542534gmail-il">at</span> <span style="background-color:rgb(255,255,255)"><b>10:30 am</b></span></font></span></font></div><div class="gmail_default" style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;text-decoration-style:initial;text-decoration-color:initial;background-color:rgb(255,255,255)"><font face="arial, helvetica, sans-serif"><span style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;text-decoration-style:initial;text-decoration-color:initial"><font color="#000000" face="arial, helvetica, sans-serif"><br></font></span></font></div><div class="gmail_default" style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;text-decoration-style:initial;text-decoration-color:initial;background-color:rgb(255,255,255)"><font face="arial, helvetica, sans-serif"><span style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;text-decoration-style:initial;text-decoration-color:initial"><font color="#000000" face="arial, helvetica, sans-serif">Where:    <span class="gmail-m_-2908798825741450181gmail-m_-4002343983082707046gmail-m_7108663852680761240gmail-m_8932996379216170455gmail-m_7943440058048769724gmail-m_6885163803304591797gmail-m_1291990161734276046gmail-m_-5366141555987907539gmail-m_7288451293410119657gmail-m_7014796927259893518gmail-m_-5237592048697853688gmail-m_-2847741945628619148gmail-m_-681226243108775954gmail-m_-4338767794047815756gmail-m_7960197898027616883gmail-m_8692226636264124041gmail-m_2794822896869921223gmail-m_7508998950622620526gmail-m_-7153355664495542534gmail-m_8421504075585210435gmail-m_3262824545120381495gmail-m_-1141671822915777344gmail-m_-7219251726624328345gmail-m_-8588148075564318222gmail-m_-8767966813928691312gmail-m_-1542318334608687154gmail-m_5717104778280916634gmail-m_4845490158781220632gmail-m_5124567205141626540gmail-m_3209361100497750746gmail-m_2953668934074478317gmail-m_-3155518689668024534m_9067904842688472155gmail-m_3071693547520408192gmail-il"><span class="gmail-m_-2908798825741450181gmail-m_-4002343983082707046gmail-m_7108663852680761240gmail-m_8932996379216170455gmail-m_7943440058048769724gmail-m_6885163803304591797gmail-m_1291990161734276046gmail-m_-5366141555987907539gmail-m_7288451293410119657gmail-m_7014796927259893518gmail-m_-5237592048697853688gmail-m_-2847741945628619148gmail-m_-681226243108775954gmail-m_-4338767794047815756gmail-m_7960197898027616883gmail-m_8692226636264124041gmail-m_2794822896869921223gmail-m_7508998950622620526gmail-m_-7153355664495542534gmail-il">TTIC</span></span>, 6045 S Kenwood Avenue, 5th Floor, Room 526</font></span></font></div><div class="gmail_default" style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;text-decoration-style:initial;text-decoration-color:initial;background-color:rgb(255,255,255)"><font face="arial, helvetica, sans-serif"><b style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;text-decoration-style:initial;text-decoration-color:initial"><font color="#000000" face="arial, helvetica, sans-serif"><br></font></b></font></div><div style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;text-decoration-style:initial;text-decoration-color:initial;background-color:rgb(255,255,255)"><font face="arial, helvetica, sans-serif"><b style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;text-decoration-style:initial;text-decoration-color:initial"><font face="arial, helvetica, sans-serif" style="color:rgb(34,34,34);font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-transform:none;white-space:normal;word-spacing:0px"><font style="color:rgb(34,34,34);font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-transform:none;white-space:normal;word-spacing:0px"><font color="#000000" style="color:rgb(34,34,34);font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-transform:none;white-space:normal;word-spacing:0px"><font face="arial, sans-serif">Who:       <span style="color:rgb(34,34,34);font-family:arial,helvetica,sans-serif;font-size:small;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;background-color:rgb(255,255,255);text-decoration-style:initial;text-decoration-color:initial;float:none;display:inline">Hosna Jabbari, <span style="color:rgb(34,34,34);font-family:arial,helvetica,sans-serif;font-size:small;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;background-color:rgb(255,255,255);text-decoration-style:initial;text-decoration-color:initial;float:none;display:inline">University of Alberta</span></span></font></font></font></font></b></font></div><div style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;text-decoration-style:initial;text-decoration-color:initial;background-color:rgb(255,255,255)"><font face="arial, helvetica, sans-serif"><b style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;text-decoration-style:initial;text-decoration-color:initial"><font face="arial, helvetica, sans-serif" style="color:rgb(34,34,34);font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-transform:none;white-space:normal;word-spacing:0px"><font style="color:rgb(34,34,34);font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-transform:none;white-space:normal;word-spacing:0px"><font color="#000000" style="color:rgb(34,34,34);font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-transform:none;white-space:normal;word-spacing:0px"><font face="arial, sans-serif"><span style="color:rgb(34,34,34);font-family:arial,helvetica,sans-serif;font-size:small;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;background-color:rgb(255,255,255);text-decoration-style:initial;text-decoration-color:initial;float:none;display:inline"><span style="color:rgb(34,34,34);font-family:arial,helvetica,sans-serif;font-size:small;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;background-color:rgb(255,255,255);text-decoration-style:initial;text-decoration-color:initial;float:none;display:inline"><br></span></span></font></font></font></font></b></font></div><p class="MsoNormal" style="margin:0in 0in 0.0001pt;color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;text-decoration-style:initial;text-decoration-color:initial;background-color:rgb(255,255,255);line-height:14.72px"><span style="line-height:14.72px"><font face="arial, helvetica, sans-serif"><font face="arial, helvetica, sans-serif" style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;background-color:rgb(255,255,255);text-decoration-style:initial;text-decoration-color:initial"><br></font></font></span></p><p class="MsoNormal" style="margin:0in 0in 0.0001pt;color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;text-decoration-style:initial;text-decoration-color:initial;background-color:rgb(255,255,255);line-height:14.72px"><span style="line-height:14.72px"><font face="arial, helvetica, sans-serif">Title:       Computational Informatics for Improving Efficacy of Gene Therapy</font></span></p><p class="MsoNormal" style="margin:0in 0in 0.0001pt;color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;text-decoration-style:initial;text-decoration-color:initial;background-color:rgb(255,255,255);line-height:14.72px"><span style="line-height:14.72px"><span><font face="arial, helvetica, sans-serif"> </font></span></span></p><p class="MsoNormal" style="margin:0in 0in 0.0001pt;color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;text-decoration-style:initial;text-decoration-color:initial;background-color:rgb(255,255,255);line-height:14.72px"><span style="line-height:14.72px"><font face="arial, helvetica, sans-serif">Abstract:  </font></span><span style="font-family:arial,helvetica,sans-serif;line-height:14.72px">With the amount of genomic data produced every day, advances in life sciences and<span> </span></span><span style="font-family:arial,helvetica,sans-serif;line-height:14.72px">development of new gene modification tools, a revolution in medicine is expected.  Recent approval of the first gene therapies by FDA is a leap towards this revolution. Computational methods provide unique opportunities<span> </span></span><span style="font-family:arial,helvetica,sans-serif;line-height:14.72px;color:rgb(26,26,26)">to realize this revolution by providing both an inexpensive framework (in terms of cost, time and safety) to explore the complex biological systems of diseases, and a reduced search space for treatment options. In this talk, I will describe an example of such framework for treatment of Duchenne muscular dystrophy through gene therapy, and highlight some of the challenges and future opportunities.</span></p><p class="MsoNormal" style="margin:0in 0in 12pt;color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;text-decoration-style:initial;text-decoration-color:initial;background-color:rgb(255,255,255);line-height:14.72px"><span style="line-height:14.72px"><font face="arial, helvetica, sans-serif"><br>Bio:  </font></span><span style="font-family:arial,helvetica,sans-serif;line-height:14.72px">Dr. Hosna Jabbari is currently a postdoctoral fellow at the Ingenuity Lab, a multidisciplinary research laboratory at the University of Alberta. Her main research goal is to help diagnose and cure human diseases by developing novel diagnostics and therapeutics through research using techniques from (algorithmic) bioinformatics, data science and computational genomics. She obtained a Ph.D.  in 2015, in computer science – bioinformatics from the University of British Columbia, advised by Anne Condon and supported by Natural Sciences and Engineering Research Council of Canada (NSERC). Hosna has served as a technical program committee for<span> </span></span><span lang="EN-CA" style="font-family:arial,helvetica,sans-serif;line-height:14.72px">the 31^st<span> </span>Association for the Advancement of Artificial Intelligence</span><span lang="EN-CA" style="font-family:arial,helvetica,sans-serif;line-height:14.72px"><span> </span></span><span style="font-family:arial,helvetica,sans-serif;line-height:14.72px">conference (AAAI 2017) and the 25^th<span> </span>International Joint Conference on AI </span><span style="font-family:arial,helvetica,sans-serif;line-height:14.72px;color:black">(IJCAI 2016).</span><br></p><p class="MsoNormal" style="margin:0in 0in 0.0001pt;color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;text-decoration-style:initial;text-decoration-color:initial;background-color:rgb(255,255,255);line-height:14.72px"><span lang="EN-CA" style="line-height:14.72px"><span><font face="arial, helvetica, sans-serif"> </font></span></span></p><p class="MsoNormal" style="margin:12pt 0in;color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;text-decoration-style:initial;text-decoration-color:initial;background-color:rgb(255,255,255);line-height:14.72px"><span style="line-height:14.72px"><font face="arial, helvetica, sans-serif"> Host:<span> </span><a href="mailto:j3xu@ttic.edu" target="_blank" style="color:rgb(17,85,204)">Jinbo Xu</a></font></span></p><br class="gmail-Apple-interchange-newline">

<br><div class="gmail_extra"><br clear="all"><div><div class="gmail_signature" data-smartmail="gmail_signature"><div dir="ltr"><div><div dir="ltr"><div><div dir="ltr"><div><div dir="ltr"><font face="arial, helvetica, sans-serif">Mary C. Marre</font><div><font face="arial, helvetica, sans-serif">Administrative Assistant</font></div><div><i><font face="arial, helvetica, sans-serif" color="#3d85c6"><b>Toyota Technological Institute</b></font></i></div><div><i><font face="arial, helvetica, sans-serif" color="#3d85c6">6045 S. Kenwood Avenue</font></i></div><div><i><font face="arial, helvetica, sans-serif" color="#3d85c6">Room 504</font></i></div><div><i><font face="arial, helvetica, sans-serif" color="#3d85c6">Chicago, IL  60637</font></i></div><div><i><font face="arial, helvetica, sans-serif">p:(773) 834-1757</font></i></div><div><i><font face="arial, helvetica, sans-serif">f: (773) 357-6970</font></i></div><div><b><i><a href="mailto:mmarre@ttic.edu" target="_blank"><font face="arial, helvetica, sans-serif">mmarre@ttic.edu</font></a></i></b></div></div></div></div></div></div></div></div></div></div>
<br><div class="gmail_quote">On Sun, Mar 11, 2018 at 7:38 PM, Mary Marre <span dir="ltr"><<a href="mailto:mmarre@ttic.edu" target="_blank">mmarre@ttic.edu</a>></span> wrote:<br><blockquote class="gmail_quote" style="margin:0 0 0 .8ex;border-left:1px #ccc solid;padding-left:1ex"><div dir="ltr">

<div class="m_-2908798825741450181gmail-gE m_-2908798825741450181gmail-iv m_-2908798825741450181gmail-gt" style="padding:10px 0px 3px;font-size:12.8px"><table cellpadding="0" class="m_-2908798825741450181gmail-cf m_-2908798825741450181gmail-gJ" style="border-collapse:collapse;margin-top:0px;width:auto"><tbody></tbody></table></div><div id="m_-2908798825741450181gmail-:18i"><div class="m_-2908798825741450181gmail-qQVYZb"></div><div class="m_-2908798825741450181gmail-utdU2e"></div><div class="m_-2908798825741450181gmail-btm"></div></div><div class="m_-2908798825741450181gmail-aHl"></div><div id="m_-2908798825741450181gmail-:18v"></div><div id="m_-2908798825741450181gmail-:18k" class="m_-2908798825741450181gmail-ii m_-2908798825741450181gmail-gt" style="font-size:12.8px;direction:ltr;margin:5px 15px 0px 0px;padding-bottom:5px"><div id="m_-2908798825741450181gmail-:18j" class="m_-2908798825741450181gmail-a3s m_-2908798825741450181gmail-aXjCH m_-2908798825741450181gmail-m161fc381476370fe" style="overflow:hidden"><div dir="ltr"><div class="m_-2908798825741450181gmail-adM" style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;background-color:rgb(255,255,255);text-decoration-style:initial;text-decoration-color:initial"></div><p class="MsoNormal" style="margin:0in 0in 0.0001pt;color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;background-color:rgb(255,255,255);text-decoration-style:initial;text-decoration-color:initial;line-height:14.72px"><span style="line-height:14.72px"><font face="arial, helvetica, sans-serif"><b style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;text-decoration-style:initial;text-decoration-color:initial"></b></font></span></p><div style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;text-decoration-style:initial;text-decoration-color:initial;background-color:rgb(255,255,255)"><font face="arial, helvetica, sans-serif"><span style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;text-decoration-style:initial;text-decoration-color:initial"><font color="#000000" face="arial, helvetica, sans-serif">When:     Monday, March 12th <span class="m_-2908798825741450181gmail-m_-4002343983082707046gmail-m_7108663852680761240gmail-m_8932996379216170455gmail-m_7943440058048769724gmail-m_6885163803304591797gmail-m_1291990161734276046gmail-m_-5366141555987907539gmail-m_7288451293410119657gmail-m_7014796927259893518gmail-m_-5237592048697853688gmail-m_-2847741945628619148gmail-m_-681226243108775954gmail-m_-4338767794047815756gmail-m_7960197898027616883gmail-m_8692226636264124041gmail-m_2794822896869921223gmail-m_7508998950622620526gmail-m_-7153355664495542534gmail-il">at</span> <span style="background-color:rgb(255,255,255)"><b>10:30 am</b></span></font></span></font></div><div style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;text-decoration-style:initial;text-decoration-color:initial;background-color:rgb(255,255,255)"><font face="arial, helvetica, sans-serif"><span style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;text-decoration-style:initial;text-decoration-color:initial"><font color="#000000" face="arial, helvetica, sans-serif"><br></font></span></font></div><div style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;text-decoration-style:initial;text-decoration-color:initial;background-color:rgb(255,255,255)"><font face="arial, helvetica, sans-serif"><span style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;text-decoration-style:initial;text-decoration-color:initial"><font color="#000000" face="arial, helvetica, sans-serif">Where:    <span class="m_-2908798825741450181gmail-m_-4002343983082707046gmail-m_7108663852680761240gmail-m_8932996379216170455gmail-m_7943440058048769724gmail-m_6885163803304591797gmail-m_1291990161734276046gmail-m_-5366141555987907539gmail-m_7288451293410119657gmail-m_7014796927259893518gmail-m_-5237592048697853688gmail-m_-2847741945628619148gmail-m_-681226243108775954gmail-m_-4338767794047815756gmail-m_7960197898027616883gmail-m_8692226636264124041gmail-m_2794822896869921223gmail-m_7508998950622620526gmail-m_-7153355664495542534gmail-m_8421504075585210435gmail-m_3262824545120381495gmail-m_-1141671822915777344gmail-m_-7219251726624328345gmail-m_-8588148075564318222gmail-m_-8767966813928691312gmail-m_-1542318334608687154gmail-m_5717104778280916634gmail-m_4845490158781220632gmail-m_5124567205141626540gmail-m_3209361100497750746gmail-m_2953668934074478317gmail-m_-3155518689668024534m_9067904842688472155gmail-m_3071693547520408192gmail-il"><span class="m_-2908798825741450181gmail-m_-4002343983082707046gmail-m_7108663852680761240gmail-m_8932996379216170455gmail-m_7943440058048769724gmail-m_6885163803304591797gmail-m_1291990161734276046gmail-m_-5366141555987907539gmail-m_7288451293410119657gmail-m_7014796927259893518gmail-m_-5237592048697853688gmail-m_-2847741945628619148gmail-m_-681226243108775954gmail-m_-4338767794047815756gmail-m_7960197898027616883gmail-m_8692226636264124041gmail-m_2794822896869921223gmail-m_7508998950622620526gmail-m_-7153355664495542534gmail-il">TTIC</span></span>, 6045 S Kenwood Avenue, 5th Floor, Room 526</font></span></font></div><div style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;text-decoration-style:initial;text-decoration-color:initial;background-color:rgb(255,255,255)"><font face="arial, helvetica, sans-serif"><b style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;text-decoration-style:initial;text-decoration-color:initial"><font color="#000000" face="arial, helvetica, sans-serif"><br></font></b></font></div><div style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;text-decoration-style:initial;text-decoration-color:initial;background-color:rgb(255,255,255)"><font face="arial, helvetica, sans-serif"><b style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;text-decoration-style:initial;text-decoration-color:initial"><font face="arial, helvetica, sans-serif" style="color:rgb(34,34,34);font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-transform:none;white-space:normal;word-spacing:0px"><font style="color:rgb(34,34,34);font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-transform:none;white-space:normal;word-spacing:0px"><font color="#000000" style="color:rgb(34,34,34);font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-transform:none;white-space:normal;word-spacing:0px"><font face="arial, sans-serif">Who:       <span style="color:rgb(34,34,34);font-family:arial,helvetica,sans-serif;font-size:small;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;background-color:rgb(255,255,255);text-decoration-style:initial;text-decoration-color:initial;float:none;display:inline">Hosna Jabbari, <span style="color:rgb(34,34,34);font-family:arial,helvetica,sans-serif;font-size:small;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;background-color:rgb(255,255,255);text-decoration-style:initial;text-decoration-color:initial;float:none;display:inline">University of Alberta</span></span></font></font></font></font></b></font></div><p class="MsoNormal" style="margin:0in 0in 0.0001pt;color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;background-color:rgb(255,255,255);text-decoration-style:initial;text-decoration-color:initial;line-height:14.72px"><span style="line-height:14.72px"><font face="arial, helvetica, sans-serif"><font face="arial, helvetica, sans-serif" style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;background-color:rgb(255,255,255);text-decoration-style:initial;text-decoration-color:initial"><br></font></font></span></p><p class="MsoNormal" style="margin:0in 0in 0.0001pt;color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;background-color:rgb(255,255,255);text-decoration-style:initial;text-decoration-color:initial;line-height:14.72px"><span style="line-height:14.72px"><font face="arial, helvetica, sans-serif">Title:       Computational Informatics for Improving Efficacy of Gene Therapy</font></span></p><p class="MsoNormal" style="margin:0in 0in 0.0001pt;color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;background-color:rgb(255,255,255);text-decoration-style:initial;text-decoration-color:initial;line-height:14.72px"><span style="line-height:14.72px"><span><font face="arial, helvetica, sans-serif"> </font></span></span></p><p class="MsoNormal" style="margin:0in 0in 0.0001pt;color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;background-color:rgb(255,255,255);text-decoration-style:initial;text-decoration-color:initial;line-height:14.72px"><span style="line-height:14.72px"><font face="arial, helvetica, sans-serif">Abstract:  </font></span><span style="font-family:arial,helvetica,sans-serif;line-height:14.72px">With the amount of genomic data produced every day, advances in life sciences and<span> </span></span><span style="font-family:arial,helvetica,sans-serif;line-height:14.72px">development of new gene modification tools, a revolution in medicine is expected.  Recent approval of the first gene therapies by FDA is a leap towards this revolution. Computational methods provide unique opportunities<span> </span></span><span style="font-family:arial,helvetica,sans-serif;line-height:14.72px;color:rgb(26,26,26)">to realize this revolution by providing both an inexpensive framework (in terms of cost, time and safety) to explore the complex biological systems of diseases, and a reduced search space for treatment options. In this talk, I will describe an example of such framework for treatment of Duchenne muscular dystrophy through gene therapy, and highlight some of the challenges and future opportunities.</span></p><p class="MsoNormal" style="margin:0in 0in 12pt;color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;background-color:rgb(255,255,255);text-decoration-style:initial;text-decoration-color:initial;line-height:14.72px"><span style="line-height:14.72px"><font face="arial, helvetica, sans-serif"><br>Bio:  </font></span><span style="font-family:arial,helvetica,sans-serif;line-height:14.72px">Dr. Hosna Jabbari is currently a postdoctoral fellow at the Ingenuity Lab, a multidisciplinary research laboratory at the University of Alberta. Her main research goal is to help diagnose and cure human diseases by developing novel diagnostics and therapeutics through research using techniques from (algorithmic) bioinformatics, data science and computational genomics. She obtained a Ph.D.  in 2015, in computer science – bioinformatics from the University of British Columbia, advised by Anne Condon and supported by Natural Sciences and Engineering Research Council of Canada (NSERC). Hosna has served as a technical program committee for<span> </span></span><span lang="EN-CA" style="font-family:arial,helvetica,sans-serif;line-height:14.72px">the 31^st<span> </span>Association for the Advancement of Artificial Intelligence</span><span lang="EN-CA" style="font-family:arial,helvetica,sans-serif;line-height:14.72px"><span> </span></span><span style="font-family:arial,helvetica,sans-serif;line-height:14.72px">conference (AAAI 2017) and the 25^th<span> </span>International Joint Conference on AI </span><span style="font-family:arial,helvetica,sans-serif;line-height:14.72px;color:black">(IJCAI 2016).</span><br></p><p class="MsoNormal" style="margin:0in 0in 0.0001pt;color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;background-color:rgb(255,255,255);text-decoration-style:initial;text-decoration-color:initial;line-height:14.72px"><span lang="EN-CA" style="line-height:14.72px"><span><font face="arial, helvetica, sans-serif"> </font></span></span></p><p class="MsoNormal" style="margin:12pt 0in;color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;background-color:rgb(255,255,255);text-decoration-style:initial;text-decoration-color:initial;line-height:14.72px"><span style="line-height:14.72px"><font face="arial, helvetica, sans-serif"> Host:<span> </span><a href="mailto:j3xu@ttic.edu" style="color:rgb(17,85,204)" target="_blank">Jinbo Xu</a></font></span></p><br class="m_-2908798825741450181gmail-Apple-interchange-newline">

</div></div></div><br><div class="gmail_extra"><br clear="all"><div><div class="m_-2908798825741450181gmail_signature" data-smartmail="gmail_signature"><div dir="ltr"><div><div dir="ltr"><div><div dir="ltr"><div><div dir="ltr"><font face="arial, helvetica, sans-serif">Mary C. Marre</font><div><font face="arial, helvetica, sans-serif">Administrative Assistant</font></div><div><i><font face="arial, helvetica, sans-serif" color="#3d85c6"><b>Toyota Technological Institute</b></font></i></div><div><i><font face="arial, helvetica, sans-serif" color="#3d85c6">6045 S. Kenwood Avenue</font></i></div><div><i><font face="arial, helvetica, sans-serif" color="#3d85c6">Room 504</font></i></div><div><i><font face="arial, helvetica, sans-serif" color="#3d85c6">Chicago, IL  60637</font></i></div><div><i><font face="arial, helvetica, sans-serif">p:<a href="tel:(773)%20834-1757" value="+17738341757" target="_blank">(773) 834-1757</a></font></i></div><div><i><font face="arial, helvetica, sans-serif">f: <a href="tel:(773)%20357-6970" value="+17733576970" target="_blank">(773) 357-6970</a></font></i></div><div><b><i><a href="mailto:mmarre@ttic.edu" target="_blank"><font face="arial, helvetica, sans-serif">mmarre@ttic.edu</font></a></i></b></div></div></div></div></div></div></div></div></div></div>
<br><div class="gmail_quote">On Tue, Mar 6, 2018 at 10:49 AM, Mary Marre <span dir="ltr"><<a href="mailto:mmarre@ttic.edu" target="_blank">mmarre@ttic.edu</a>></span> wrote:<br><blockquote class="gmail_quote" style="margin:0 0 0 .8ex;border-left:1px #ccc solid;padding-left:1ex"><div dir="ltr">


















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<b style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;text-decoration-style:initial;text-decoration-color:initial"></b></font></span></p><div style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;background-color:rgb(255,255,255);text-decoration-style:initial;text-decoration-color:initial"><font face="arial, helvetica, sans-serif"><b style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;text-decoration-style:initial;text-decoration-color:initial"><font color="#000000" face="arial, helvetica, sans-serif">When:     Monday, March 12th <span class="m_-2908798825741450181m_-4002343983082707046gmail-m_7108663852680761240gmail-m_8932996379216170455gmail-m_7943440058048769724gmail-m_6885163803304591797gmail-m_1291990161734276046gmail-m_-5366141555987907539gmail-m_7288451293410119657gmail-m_7014796927259893518gmail-m_-5237592048697853688gmail-m_-2847741945628619148gmail-m_-681226243108775954gmail-m_-4338767794047815756gmail-m_7960197898027616883gmail-m_8692226636264124041gmail-m_2794822896869921223gmail-m_7508998950622620526gmail-m_-7153355664495542534gmail-il">at</span> <b style="background-color:rgb(255,255,255)">10:30 am</b></font></b></font></div><div style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;background-color:rgb(255,255,255);text-decoration-style:initial;text-decoration-color:initial"><font face="arial, helvetica, sans-serif"><b style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;text-decoration-style:initial;text-decoration-color:initial"><font color="#000000" face="arial, helvetica, sans-serif"><br></font></b></font></div><div style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;background-color:rgb(255,255,255);text-decoration-style:initial;text-decoration-color:initial"><font face="arial, helvetica, sans-serif"><b style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;text-decoration-style:initial;text-decoration-color:initial"><font color="#000000" face="arial, helvetica, sans-serif">Where:    <span class="m_-2908798825741450181m_-4002343983082707046gmail-m_7108663852680761240gmail-m_8932996379216170455gmail-m_7943440058048769724gmail-m_6885163803304591797gmail-m_1291990161734276046gmail-m_-5366141555987907539gmail-m_7288451293410119657gmail-m_7014796927259893518gmail-m_-5237592048697853688gmail-m_-2847741945628619148gmail-m_-681226243108775954gmail-m_-4338767794047815756gmail-m_7960197898027616883gmail-m_8692226636264124041gmail-m_2794822896869921223gmail-m_7508998950622620526gmail-m_-7153355664495542534gmail-m_8421504075585210435gmail-m_3262824545120381495gmail-m_-1141671822915777344gmail-m_-7219251726624328345gmail-m_-8588148075564318222gmail-m_-8767966813928691312gmail-m_-1542318334608687154gmail-m_5717104778280916634gmail-m_4845490158781220632gmail-m_5124567205141626540gmail-m_3209361100497750746gmail-m_2953668934074478317gmail-m_-3155518689668024534m_9067904842688472155gmail-m_3071693547520408192gmail-il"><span class="m_-2908798825741450181m_-4002343983082707046gmail-m_7108663852680761240gmail-m_8932996379216170455gmail-m_7943440058048769724gmail-m_6885163803304591797gmail-m_1291990161734276046gmail-m_-5366141555987907539gmail-m_7288451293410119657gmail-m_7014796927259893518gmail-m_-5237592048697853688gmail-m_-2847741945628619148gmail-m_-681226243108775954gmail-m_-4338767794047815756gmail-m_7960197898027616883gmail-m_8692226636264124041gmail-m_2794822896869921223gmail-m_7508998950622620526gmail-m_-7153355664495542534gmail-il">TTIC</span></span>, 6045 S Kenwood Avenue, 5th Floor, Room 526</font></b></font></div><div style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;background-color:rgb(255,255,255);text-decoration-style:initial;text-decoration-color:initial"><font face="arial, helvetica, sans-serif"><b style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;text-decoration-style:initial;text-decoration-color:initial"><font color="#000000" face="arial, helvetica, sans-serif"><br></font></b></font></div><div style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;background-color:rgb(255,255,255);text-decoration-style:initial;text-decoration-color:initial"><font face="arial, helvetica, sans-serif"><b style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;text-decoration-style:initial;text-decoration-color:initial"><font face="arial, helvetica, sans-serif" style="color:rgb(34,34,34);font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-transform:none;white-space:normal;word-spacing:0px"><font style="color:rgb(34,34,34);font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-transform:none;white-space:normal;word-spacing:0px"><font color="#000000" style="color:rgb(34,34,34);font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-transform:none;white-space:normal;word-spacing:0px"><font face="arial, sans-serif">Who:       <span style="color:rgb(34,34,34);font-family:arial,helvetica,sans-serif;font-size:small;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;background-color:rgb(255,255,255);text-decoration-style:initial;text-decoration-color:initial;float:none;display:inline">Hosna Jabbari, <span style="color:rgb(34,34,34);font-family:arial,helvetica,sans-serif;font-size:small;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;background-color:rgb(255,255,255);text-decoration-style:initial;text-decoration-color:initial;float:none;display:inline">University of Alberta</span>

</span></font></font></font></font></b></font></div><font face="arial, helvetica, sans-serif"><b style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;text-decoration-style:initial;text-decoration-color:initial"><font face="arial, helvetica, sans-serif" style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;background-color:rgb(255,255,255);text-decoration-style:initial;text-decoration-color:initial"></font></b><font face="arial, helvetica, sans-serif" style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;background-color:rgb(255,255,255);text-decoration-style:initial;text-decoration-color:initial"><br class="m_-2908798825741450181m_-4002343983082707046gmail-Apple-interchange-newline"></font></font><p></p><p class="MsoNormal" style="line-height:115%;margin:0in 0in 0.0001pt"><span style="line-height:115%"><font face="arial, helvetica, sans-serif"><font face="arial, helvetica, sans-serif" style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;background-color:rgb(255,255,255);text-decoration-style:initial;text-decoration-color:initial"><br></font></font></span></p><p class="MsoNormal" style="line-height:115%;margin:0in 0in 0.0001pt"><span style="line-height:115%"><font face="arial, helvetica, sans-serif">Title:       Computational Informatics
for Improving Efficacy of Gene Therapy</font></span></p>

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<p class="MsoNormal" style="line-height:115%;margin:0in 0in 0.0001pt"><span style="line-height:115%"><font face="arial, helvetica, sans-serif">Abstract:  </font></span><span style="font-family:arial,helvetica,sans-serif;line-height:115%">With the amount of
genomic data produced every day, advances in life sciences and </span><span style="font-family:arial,helvetica,sans-serif;line-height:115%">development of new gene modification tools, a
revolution in medicine is expected. 
Recent approval of the first gene therapies by FDA is a leap towards
this revolution. Computational methods provide unique opportunities </span><span style="font-family:arial,helvetica,sans-serif;line-height:115%;color:rgb(26,26,26)">to realize this revolution by
providing both an inexpensive framework (in terms of cost, time and safety) to
explore the complex biological systems of diseases, and a reduced search space
for treatment options. In this talk, I will describe an example of such
framework for treatment of Duchenne muscular dystrophy through gene therapy,
and highlight some of the challenges and future opportunities.</span></p>

<p class="MsoNormal" style="margin:0in 0in 12pt;line-height:115%"><span style="line-height:115%"><font face="arial, helvetica, sans-serif"><br>Bio:  </font></span><span style="font-family:arial,helvetica,sans-serif;line-height:115%">Dr.
Hosna Jabbari is currently a postdoctoral fellow at the Ingenuity Lab, a
multidisciplinary research laboratory at the University of Alberta. Her main
research goal is to help diagnose and cure human diseases by developing novel
diagnostics and therapeutics through research using techniques from
(algorithmic) bioinformatics, data science and computational genomics. She obtained
a Ph.D.  in 2015, in computer science –
bioinformatics from the University of British Columbia, advised by Anne Condon
and supported by Natural Sciences and Engineering Research Council of Canada (NSERC).
Hosna has served as a technical program committee for </span><span lang="EN-CA" style="font-family:arial,helvetica,sans-serif;line-height:115%">the 31^st Association for the Advancement of
Artificial Intelligence</span><span lang="EN-CA" style="font-family:arial,helvetica,sans-serif;line-height:115%"> </span><span style="font-family:arial,helvetica,sans-serif;line-height:115%">conference
(AAAI 2017) and the 25^th International Joint Conference on AI </span><span style="font-family:arial,helvetica,sans-serif;line-height:115%;color:black">(IJCAI
2016).</span><br></p>

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<p class="MsoNormal" style="margin:12pt 0in;line-height:115%"><span style="line-height:115%"><font face="arial, helvetica, sans-serif"> Host: <a href="mailto:j3xu@ttic.edu" target="_blank">Jinbo Xu</a></font></span></p>





<div><br></div><div><br></div><div><br></div><br clear="all"><div><div class="m_-2908798825741450181m_-4002343983082707046gmail_signature" data-smartmail="gmail_signature"><div dir="ltr"><div><div dir="ltr"><div><div dir="ltr"><div><div dir="ltr"><font face="arial, helvetica, sans-serif">Mary C. Marre</font><div><font face="arial, helvetica, sans-serif">Administrative Assistant</font></div><div><i><font face="arial, helvetica, sans-serif" color="#3d85c6"><b>Toyota Technological Institute</b></font></i></div><div><i><font face="arial, helvetica, sans-serif" color="#3d85c6">6045 S. Kenwood Avenue</font></i></div><div><i><font face="arial, helvetica, sans-serif" color="#3d85c6">Room 504</font></i></div><div><i><font face="arial, helvetica, sans-serif" color="#3d85c6">Chicago, IL  60637</font></i></div><div><i><font face="arial, helvetica, sans-serif">p:<a href="tel:(773)%20834-1757" value="+17738341757" target="_blank">(773) 834-1757</a></font></i></div><div><i><font face="arial, helvetica, sans-serif">f: <a href="tel:(773)%20357-6970" value="+17733576970" target="_blank">(773) 357-6970</a></font></i></div><div><b><i><a href="mailto:mmarre@ttic.edu" target="_blank"><font face="arial, helvetica, sans-serif">mmarre@ttic.edu</font></a></i></b></div></div></div></div></div></div></div></div></div></div>
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