<html><body style="word-wrap: break-word; -webkit-nbsp-mode: space; -webkit-line-break: after-white-space; ">DEPARTMENT OF COMPUTER SCIENCE<div><br class="webkit-block-placeholder"></div><div>UNIVERSITY OF CHICAGO</div><div><br class="webkit-block-placeholder"></div><div>Date: Wednesday, April 16, 2008</div><div>Time: 12:00 p.m.</div><div>Place: Kent 120, 1020 E. 58th Street</div><div><br class="webkit-block-placeholder"></div><div>----------------------------------------------------------</div><div><br class="webkit-block-placeholder"></div><div>Speaker:<span class="Apple-tab-span" style="white-space: pre; ">        </span>Eric Vigoda</div><div><br class="webkit-block-placeholder"></div><div>From:<span class="Apple-tab-span" style="white-space: pre; ">                </span>Georgia Institute of Technology</div><div><br class="webkit-block-placeholder"></div><div>Web page:<span class="Apple-tab-span" style="white-space: pre; ">        </span><a href="http://www.cc.gatech.edu/~vigoda/">http://www.cc.gatech.edu/~vigoda/</a></div><div><br class="webkit-block-placeholder"></div><div>Title:&nbsp;<span class="Apple-style-span" style="font-family: 'Times New Roman'; font-size: 16px; "><font class="Apple-style-span" face="Helvetica" size="3"><span class="Apple-style-span" style="font-size: 12px;">Markov Chain Monte Carlo
Algorithms</span></font><span style="color:black"><span style="mso-tab-count:1"><font class="Apple-style-span" face="Helvetica" size="3"><span class="Apple-style-span" style="font-size: 12px;">&nbsp;</span></font>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp;&nbsp;</span></span></span></div><!--StartFragment--><div><br class="webkit-block-placeholder"></div><div>Abstract:&nbsp;In this talk, I'll look at the design and analysis of
Markov Chain Monte Carlo (MCMC) algorithms. &nbsp;In the first part of the talk
I will present MCMC algorithms&nbsp;which yielded the first polynomial-time
algorithms for important combinatorial problems. &nbsp;In particular, I'll present
MCMC algorithms for sampling/counting 0-1 contingency tables with arbitrary
row/column sums, and estimating the&nbsp;permanent of a non-negative matrix. &nbsp;These algorithms
require a sophisticated simulated annealing type approach, with a sequence of
problem instances starting from a trivial instance (infinite temperature)&nbsp;and slowly moving to the instance of interest (zero
temperature).&nbsp;</div><p class="MsoNormal" style="mso-pagination:none;mso-layout-grid-align:none; text-autospace:none"><o:p></o:p></p>

<span style="">In the second part of the talk I will discuss
the use of MCMC algorithms in evolutionary biology for phylogenetic reconstruction.
&nbsp;I'll present some recent work in that setting where heterogeneous data
causes the MCMC algorithms to be slow to converge to the desired posterior
distribution.</span><!--EndFragment-->



<p class="MsoNormal">---------------------------------------------------------</p><p class="MsoNormal">Host:<span class="Apple-tab-span" style="white-space: pre; ">        </span>Stuart Kurtz</p></body></html>