[Colloquium] Talks at TTIC: Daifeng Wang, Yale University

[Dawn Ellis]

When:     Monday, April 27th at 11am

Where:    TTIC, 6045 S Kenwood Avenue, 5th Floor, Room 526

Who:       Daifeng Wang, Yale University

Title:       Systems analysis of gene regulation

Abstract:

The rapidly increasing quantity of biological data offers novel and diverse
resources to study biological functions at the system level. Integrating
and mining these various large-scale datasets is both a central priority
and a great challenge for the field of systems biology. Achieving this
ambitious goal necessitates the development of specialized computational
approaches. In this talk, I will present three novel computational
approaches to study gene expression and regulation with applications to
developmental biology, biomedicine and bioenergy: 1) an algorithm to
simultaneously cluster gene co-expression networks across multiple species,
discovering the conserved and species-specific gene and non-coding RNA
modules along with their developmental hourglass behaviors; 2) a
logic-circuit based method to identify the genome-wide logical
cooperativity among gene regulatory factors; 3) an integrated method using
the state-space model and dimensionality reduction to identify principal
gene expression dynamic patterns driven by different subsystems of a gene
regulatory network. In addition, I will discuss the future directions where
computational and bioinformatics approaches can make a significant impact
in systems biology.

**********************************

Host:  Jinbo Xu, j3xu at ttic.edu
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-- 
*Dawn Ellis*
Administrative Coordinator,
Bookkeeper
773-834-1757
dellis at ttic.edu <javascript:_e(%7B%7D,'cvml','dellis at ttic.edu');>

TTIC
6045 S. Kenwood Ave.
Chicago, IL. 60637


-- 
*Dawn Ellis*
Administrative Coordinator,
Bookkeeper
773-834-1757
dellis at ttic.edu

TTIC
6045 S. Kenwood Ave.
Chicago, IL. 60637
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