Talk on Friday, 10 November - Guenter Tusch
Margery Ishmael
marge at cs.uchicago.edu
Tue Nov 7 10:31:09 CST 2000
Department of Computer Science/The University of Chicago
Ryerson Hall -- 1100 E. 58th Street
COLLOQUIUM ANNOUNCEMENT
Friday, 10 November at 2:30 pm in Ryerson (Annex) 276
(To be followed by refreshments in Ryerson 255)
Guenter Tusch
Title: 'Optimal sequential decisions based on a POMDP model - application
to liver transplantation'.
Abstract: Sequential decision making is investigated in different fields as
robotics, economics, or medicine. The present investigation aims at the
construction of a sequential decision procedure derived from a partially
observable Markov decision process (POMDP) model. An optimal clinical
management strategy based on a risk assessment of patients is to be found.
A decision theoretic cost model different from the general approach has
been selected for this clinical management (and classification) task: costs
were determined by specifying a minimum acceptable sensitivity and
specificity of the overall procedure. The aim is to construct a decision
procedure to determine if a patient is a high risk patient or not and to
estimate the probabilities that are necessary for the model from clinical
data. This is achieved by finding the earliest possible decision epoch
where a final decision can be made under these quality restrictions.
Solution method is non-linear optimization combined with
a robust partial classification method. The probabilities necessary for the
model are estimated from data of a clinical study in liver transplantation
patients. Decision epochs were at donor organ assessment, immediately
before surgery and post operatively in the intensive care unit. Parameters
obtained within decision epochs were combined to scores by artificial
neural networks (ANNs). The encouraging results show the applicability of
the model in the clinical setting.
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end abstract
If you'd like to make an appointment to speak to Guenter Tusch, please
contact marge at cs.uchicago.edu
====================================================
Margery Ishmael
Department of Computer Science
1100 E. 58th St.
Chicago, IL 60637
tel: 773 834-8977 fax: 773 702-8487
marge at cs.uchicago.edu
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